Personalized medicine in chronic kidney disease by detection of monogenic mutations

DM Connaughton, F Hildebrandt - Nephrology Dialysis …, 2020 - academic.oup.com
… of the following markers of kidney damage: albuminuria, urine sediment abnormalities,
electrolyte and other abnormalities due to tubular disorders, abnormalities detected by histology …

[HTML][HTML] Personalized medicine: recent progress in cancer therapy

V Gambardella, N Tarazona, JM Cejalvo, P Lombardi… - Cancers, 2020 - mdpi.com
… improved clinical outcomes in patients diagnosed with advanced melanoma. These
represent only a few examples of the application of precision medicine in daily clinical practice. …

[HTML][HTML] New perspective in diabetic neuropathy: from the periphery to the brain, a call for early detection, and precision medicine

H Yang, G Sloan, Y Ye, S Wang, B Duan… - Frontiers in …, 2020 - frontiersin.org
… the diagnostic techniques which may aid the early detection of DPN in the clinical and
research environment, and recent advances in precision medicine techniques for the treatment of …

Epidemiology of atrial fibrillation in the 21st century: novel methods and new insights

J Kornej, CS Börschel, EJ Benjamin… - Circulation …, 2020 - Am Heart Assoc
Precision medicine approaches are needed to identify individuals at higher risk for AF and …
Chronic Kidney Disease Albuminuria, mild renal impairment, and declining renal function are …

[HTML][HTML] Polygenic risk scores in the clinic: new perspectives needed on familiar ethical issues

ACF Lewis, RC Green - Genome Medicine, 2021 - Springer
… The concept of a disease It is part of the hope of precision medicine that disease classification
is refined. In this vision, the broad definitions we have of conditions, based on symptoms …

[HTML][HTML] Therapeutic approach to Alzheimer's disease: Current treatments and new perspectives

T Pardo-Moreno, A González-Acedo… - Pharmaceutics, 2022 - mdpi.com
… progression of disease symptoms and brain atrophy was also observed compared to the
control group, as well as numerous side effects including skin cancer and renal dysfunction [78]…

Treating systemic lupus erythematosus in the 21st century: new drugs and new perspectives on old drugs

G Ruiz-Irastorza, G Bertsias - Rheumatology, 2020 - academic.oup.com
treatment, glucocorticoids and immunosuppressive drugs. However, these regimens are not
universally effective and a substantial degree of damage … of treatment is individualized but …

Screening for diabetic retinopathy: new perspectives and challenges

S Vujosevic, SJ Aldington, P Silva… - The Lancet Diabetes & …, 2020 - thelancet.com
… cases that need timely full ophthalmic examination and treatment to avoid permanent visual
loss. In the past few years, personalised screening intervals that take into account several …

[HTML][HTML] Fresh insights into glucocorticoid-induced diabetes mellitus and new therapeutic directions

JX Li, CL Cummins - Nature Reviews Endocrinology, 2022 - nature.com
diagnostic criteria and treatment options based on the type and schedule of glucocorticoid
and the degree of hyperglycaemia established. Finally, we provide novel insightsdrugs while …

Rationale and design of the kidney precision medicine project

IH de Boer, CE Alpers, EU Azeloglu, UGJ Balis… - Kidney international, 2021 - Elsevier
… This investigation focuses on kidney diseases that are most prevalent and therefore … this
work include developing new mechanism-based subtypes of kidney diseases that are common …